Acne

Understanding Hormonal Acne: Causes, Treatments, and Prevention

September 9, 2024

Summary

Hormonal acne is a type of acne influenced by hormone fluctuations, particularly androgens such as testosterone.

These fluctuations can increase sebum production, clogged pores, and inflammation, resulting in acne. Hormonal acne is prevalent, affecting around 1 in 10 women, and it can occur at any stage of life, from puberty to menopause.

In addition, factors like insulin resistance, diet, gluten sensitivity, and disruptions in the skin microbiome can contribute to the severity of hormonal imbalances and, consequently, acne.

Understanding these interconnected causes is essential for effectively managing hormonal acne and promoting healthier skin.

woman with cream on face

Recognizing the Causes: A Deep Dive into the Science

Hormonal acne primarily results from changes in hormone levels, especially androgens, which stimulate the sebaceous glands to produce excess sebum. When there is an overproduction of sebum, it can mix with dead skin cells and clog pores, leading to acne outbreaks. Research has identified several key hormonal factors that contribute to acne:

1. Androgens and Sebum Production: Androgens, like testosterone, play a significant role in stimulating sebaceous gland activity. Higher levels of androgens increase sebum production, creating an environment conducive to acne development. This is particularly relevant for individuals with conditions like polycystic ovary syndrome (PCOS), which is often characterized by elevated androgens, explaining why people with PCOS are more prone to acne.

2. Insulin Resistance and PCOS: Insulin resistance is closely linked to hormonal acne. Elevated insulin levels can increase androgen production, leading to excess sebum and worsening acne. This relationship is particularly evident in PCOS, where insulin resistance frequently coexists with high androgen levels, exacerbating acne symptoms.

3. Endocrine Aspects of Acne: Various hormonal imbalances, particularly those involving the adrenal glands, can also contribute to acne. Remember that hormones are interconnected and can influence each other's production and activity. This interconnectedness is why hormonal shifts—such as those occurring during stress, the menstrual cycle, pregnancy, or menopause—can trigger or worsen acne by increasing androgen levels, promoting sebum production, and causing inflammation.

4. The Role of the Skin Microbiome: Recent research highlights the importance of the skin microbiome in acne development. Imbalances in the microbiome, including an overgrowth of acne-causing bacteria and a reduction in beneficial bacteria, may exacerbate acne symptoms. Factors such as antibiotic use, diet, and hormonal changes can disrupt this delicate balance, potentially worsening. 

Lifestyle Changes and Natural Remedies

Adopting specific lifestyle changes can significantly influence the management of hormonal acne! Here are some diet and natural remedy tips to help prevent and heal acne from the inside out:

Acne-Friendly Diet: How to Prevent and Heal Acne from the Inside

1. Keep It Low Glycemic Load: Following a high-protein and high-to-moderate-fat diet and choosing carbohydrate sources with a low glycemic index—such as vegetables, lower-sugar fruits, whole grains, and legumes—can help regulate blood sugar levels and reduce insulin spikes. Studies suggest that lower insulin levels may help decrease androgen production, which is crucial for managing acne.

2. Omega-3 Fatty Acids: Omega-3s, found primarily in fatty fish like wild-caught salmon, sardines, and mackerel, as well as algae, flaxseeds, chia seeds, and walnuts, have anti-inflammatory properties that can help calm skin inflammation associated with acne.

3. Zinc-Rich Foods: Zinc, present in foods like oysters, beef, high-quality dark chocolate, chickpeas, pumpkin seeds, and cashews, has been shown to help reduce acne by regulating oil production. Zinc is a powerful anti-inflammatory mineral, and supplementation may also be beneficial. However, zinc supplements should only be taken short-term, as they can block copper absorption. Always consult with your healthcare provider before starting any new supplements.

4. Antioxidant-Rich Foods: The popular saying "eat the rainbow" is a foundational element of the anti-acne diet. Different colored foods correspond to specific antioxidants, which help protect the skin from damage and reduce inflammation. Incorporating a wide variety of colorful fruits and vegetables can provide these protective benefits.

Foods That May Exacerbate Acne: What to Avoid

1. Dairy Products: Research indicates a link between dairy consumption—especially cow’s skim milk—and an increased risk of acne. Dairy may elevate insulin levels and insulin-like growth factor (IGF-1), promoting sebum production and inflammation, which can worsen acne.

2. High-Glycemic Foods: Foods high in refined sugars and carbohydrates, such as white bread, pastries, and sugary drinks, can cause rapid spikes in blood sugar and insulin levels, increasing androgen production and worsening acne. 

3. Processed and Fast Foods: Foods like chips, burgers, and other fast foods are often high in unhealthy fats and sugars, which can trigger inflammation and exacerbate acne.

4. Excessive Caffeine and Alcohol: While moderate consumption of caffeine may not significantly impact everyone, high intake of caffeine and alcohol has been shown to disrupt hormonal balance and gut health, potentially worsening or triggering acne.

5. Consider Gluten Sensitivity: Gluten sensitivity may contribute to acne in some people by triggering inflammation. A gluten-free diet could help reduce inflammation and improve skin health for those affected. Keep in mind that symptoms of food sensitivity can appear up to 72 hours after ingestion, making them harder to identify. 

Herbal Remedies

Certain herbal remedies may also help balance hormones and reduce acne. For example, spearmint tea, has anti-androgenic properties that may help lower testosterone levels, and evening primrose oil has been suggested to balance hormones and reduce skin inflammation. However, more research is needed to establish their efficacy fully, so consult with a healthcare provider before starting any herbal remedies.

Oral Medication for Acne: Pros and Downsides

Oral medications are commonly prescribed to manage hormonal acne, but each comes with its own benefits and potential drawbacks:

1. Birth Control Pills (OCPs): Birth control pills are often prescribed to regulate hormones and reduce androgen levels, which can help improve acne in the short term. However, these effects are temporary and do not address underlying causes like insulin resistance or inflammation. OCPs may also increase the risk of nutritional deficiencies—such as lower levels of folate, vitamin B6, and vitamin B12 and some minerals—which are essential for hormonal health. Additionally, they can disrupt natural hormonal balance, and stopping them may cause a rebound effect, potentially worsening acne or other hormonal symptoms.

2. Anti-Androgens (e.g., Spironolactone): Spironolactone works by blocking androgen receptors, thereby reducing sebum production. It has been shown to be effective in treating hormonal acne, especially in women with elevated androgen levels. However, it may cause side effects such as menstrual irregularities, breast tenderness, and elevated potassium levels (hyperkalemia), which require regular monitoring by a healthcare provider. 

3. Antibiotics: Antibiotics can be prescribed to reduce bacterial growth and inflammation associated with acne. However, they are not a sustainable long-term solution due to the risk of developing antibiotic resistance. Overuse of antibiotics can disrupt the gut and the skin microbiome, potentially leading to an imbalance that can worsen acne in the long term. Indeed, antibiotics may reduce beneficial bacteria while promoting the growth of antibiotic-resistant strains, highlighting the need for careful and limited use of antibiotics in acne treatment.

Advanced Treatment Options

For more persistent cases of hormonal acne, advanced treatment options may be considered:

1. Retinoids: Both topical and oral retinoids, such as isotretinoin, are powerful medications that reduce oil production and prevent clogged pores. While effective, they are associated with side effects like skin dryness, irritation, and birth defects, necessitating strict medical supervision. 

2. Laser and Light Therapies: These therapies target acne-causing bacteria and reduce oil production. Although effective for some, they are generally more expensive and may require multiple sessions. 

Closing Paragraph

Hormonal acne is a complex condition influenced by various factors, including hormone fluctuations, insulin resistance, dietary choices, and the balance of the skin microbiome. Understanding these underlying causes can empower you to take targeted steps toward clearer skin. By adopting lifestyle changes like a low-glycemic diet, considering potential triggers such as dairy or gluten, supporting the skin with nutrient-rich foods, and maintaining a healthy skin microbiome, you can address acne from the inside out. Remember, while medications like birth control pills or antibiotics can provide temporary relief, they may not tackle the root cause and could have additional side effects. If you’re struggling with hormonal acne, consider using the Muse Hormone Test and targeted interventions such as lifestyle changes, nutrition, and supplements, such as the Muse Treatment Plan to gain a deeper understanding of your health and find a functional treatment plan that works for you. 

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